Under steady state conditions it is straight-forward to estimate s and d. Otherwise, the total levels at some other time point are needed.

## Arguments

- ntr
the new to total RNA ratio (measured)

- total
the total level of RNA (measured)

- t
the labeling duration

- t0
time before measurement at which f0 is total level (only necessary under non-steady-state conditions)

- f0
total level at t0 (only necessary under non-steady-state conditions)

- full.return
also return the provided parameters